Opsoclonus-myoclonus

Opsoclonus myoclonus, or Kinsburn's encephalopathy, is an autoimmune disease of the central nervous system in which the cerebellum and its connections are affected. The pathology is also called "dancing" eye syndrome because of the chaotic movement of the eyeballs. Other characteristic signs include myoclonic contractions of different muscle groups as well as movement coordination disorders.

This neurological syndrome is rarely diagnosed. Children are more often affected than adults, and girls and boys are equally susceptible to the pathology.

Symptoms

Among the characteristic signs of the disease is opsoclonus, which is manifested by chaotic and rapid movements of the eyeballs horizontally, vertically, or in a circle. Opsoclonus is often accompanied by rapid movements of the eyelids.

The patient is also disturbed by myoclonic twitches of the limbs or body muscles. Sudden muscle contractions can affect the lips, eyelids, and other parts of the face. Other symptoms of the disease include:
    • impairment of movement coordination;
    • excessive excitability;
    • problems with sleep, insomnia;
    • aggressiveness;
    • sudden change of mood;
    • tremors, etc.

If you find at least some of these symptoms, you should immediately contact your doctor for a consultation.

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Causes of occurrence

The causes can be divided into two main groups:
    1. Infectious. Epstein-Barr virus, acute respiratory viral infections, and salmonella can provoke the development of opsoclonus-myoclonus syndrome. The first neurological abnormalities appear 7-10 days after an infectious disease.
    2. Tumors. In children, opsoclonus myoclonus develops against the background of neuroblastoma or ganglioneuroblastoma. In adults, lung, ovarian, and mammary gland cancer can cause the pathology.

In adults, this autoimmune encephalitis can also be triggered by vaccination. The provoking factor (virus, vaccination, tumor) stimulates the production of antibodies against brain cells.

Diagnostic methods

The VIVERE CLINIC medical center uses a comprehensive approach to diagnosing opsoclonus myoclonus syndrome. The examination program includes laboratory tests, ultrasonography, magnetic resonance imaging, and other techniques. Through a comprehensive examination, doctors at the clinic are able to differentiate diseases with similar symptoms and establish the cause of Kinsburn's encephalopathy, and then select the etiological treatment. 

Prevention

Opsoclonus myoclonus is a rare disease, so it has not yet been adequately studied. For this reason, there are no clear recommendations on how to prevent the development of the pathology. However, it is known for sure that early diagnosis helps to start therapy in time and reduce the risk of complications.

Treatment of opsoclonus myoclonus

There is currently no approved protocol for the treatment of Myoclonus opsoclonus. The doctors at the VIVERE CLINIC select the therapy for each patient individually. They take into account the clinical picture, the causes of occurrence, and the individual characteristics of the patient. 
Therapy is not just aimed at alleviating symptoms, but first and foremost at eliminating the cause.

Recommendations

When signs of myoclonus optoclonus are detected, make an appointment at the VIVERE CLINIC right away, because it is easier to treat in its early stages. If you seek qualified medical care without delay, the risk of serious complications can be reduced. It is worth remembering that only highly qualified doctors can make an accurate diagnosis and choose an effective treatment.

Cost

At VIVERE CLINIC, patients have access to the innovative diagnostic services necessary for accurate diagnosis, effective therapy, and good health. The price of a comprehensive examination depends on the methods used and is determined individually. You can find out the cost of individual procedures during an initial consultation or from our administrators.
You can make an appointment at the VIVERE CLINIC by phone or through the online form on the website.

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