Multiple Sclerosis

Multiple sclerosis is a chronic autoimmune disease characterized by multiple foci of demyelination in the brain and spinal cord.  Normal nerve tissue is replaced by connective tissue, which leads to serious neurological and mental disorders.
Among demyelinating diseases, multiple sclerosis is the most common. Today, the pathology affects more than 2 million people worldwide. The peak of morbidity is in the period of 30-50 years, but MS is diagnosed even in children and adolescents.

Symptoms

Multiple sclerosis is accompanied by a variety of neurological symptoms and is characterized by periodic exacerbations and remissions. Among the most common manifestations of MS are:
    • paresthesias in one or more extremities – sensory disturbances, discomfort, numbness, a feeling of heat, and crawling goosebumps;
    • visual disturbances – decreased visual acuity, pain, double vision;
    • weakness in an arm or leg;
    • dizziness;
    • rapid fatigue;
    •  emotional fluctuations;
    •  change in gait;
    • cognitive disorders – impaired concentration, the tendency to apathy, depression.

Most patients also have problems with urination – false urges, incontinence or retention, difficulty in starting to urinate.
If any of these signs occur, make an appointment to see a doctor and be examined. Early diagnosis can increase remission periods and slow down the progression of the disease.

For an appointment or consultation, call:

Reasons

Multiple sclerosis is caused by combinations of different factors. The immune system attacks its own nervous system cells, including those that synthesize myelin, due to a defense mechanism malfunction.

Factors that increase the risk of developing multiple sclerosis:
    • Frequent and severe stress;
    • autoimmune diseases;
    • smoking, alcohol abuse;
    • Infectious diseases (especially viral infections).

Diagnostic methods

At the VIVERE CLINIC, multiple sclerosis is diagnosed and treated by leading specialists in neuroimmunology. For an accurate diagnosis, clinical criteria are taken into account and the following examinations are used:
    • MRI of the spinal cord and brain;
    • a liquor test for oligoclonal IgG, anti-MOG antibodies, antibodies to aquaporin-4;
    • blood tests for PCR and antibodies to viruses (herpetic group, Borrelia, toxoplasma, etc.).
All examinations, including specific analyses of various biological fluids, can be performed in our clinic.

Prevention

It is recommended to exclude alcohol and smoking, to treat viral and bacterial infections, and to minimize stress.

Multiple Sclerosis Treatment at the VIVERE CLINIC

Our extensive clinical experience allows our physicians to accurately interpret the results of specific tests, find the exact cause of the disease, and influence it using modern methods. This makes it possible to achieve stable remission, slow down the progression of demyelination, and provide the patient with a high quality of life.
Treatment includes two types of therapy depending on the phase of the disease:
    • control of an exacerbation;
    • permanent disease-modifying therapy.
At the VIVERE CLINIC, patients can receive treatment on an outpatient basis or in a day hospital and receive specific therapy. The correct choice of medications and their dosage can reduce the frequency of exacerbations, alleviate clinical symptoms, achieve stable remission (sometimes lasting up to 10 years), and prevent severe complications, including those that lead to disability.

Recommendations

Multiple sclerosis is a chronic disease that cannot be completely cured. However, the selection of the correct therapy allows controlling the pathology and providing the patient with a high quality of life. Therefore, when the first signs of the disease appear, do not delay seeking medical help.

Cost

The price is based on several factors, in particular, it depends on the examination program, the need for additional tests, and methods of treatment. The cost of individual services can be clarified over the phone with a manager or with the doctor during an appointment.
You can make an appointment to see a specialist in our medical center through a form on our website or by phone. 

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Our mission is to change attitudes toward «doomed» diagnoses and to give each patient hope and a chance for a full and high-quality life.

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Протягом останнього року консультувалися з Макаром Васильовичем Шейко з приводу діагнозу та подальшої тактики лікування доньки. Отримали вичерпні відповіді на свої запитання, та насправді кваліфіковану допомогу. Можу сміливо радити лікаря як фахівця, що призначить лише потрібний обсяг досліджень, максимально глибоко та експертно оцінить результати - вважаю, саме в цьому полягає основна цінність консультації. І найголовніше - при зовнішній стриманості та небагатослівності, Макар Васильович дійсно переймається результатом лікування і прагне допомогти дитині, а не просто призначити препарати за протоколом. Щиро вдячна лікарю та клініці, сподіваюсь, з Вашою допомогою зможемо отримати добрі результати.

Світлана

Хочеться щиро подякувати Шейко Макару Васильовичу! За допомогу в вирішенні, лікуванні та правильному встановленню діагнозу нашої хвороби! Бо як виявилось сама більша проблема в тому щоб правильно встановити саме діагноз. Пред історія така .В дитини (14 років) в один прекрасний день опускається повіка, діагнозів в Охматдиті нам ставили багато, робили безліч обстежень але все марно ,поки шукали підтвердження, повіка самостійно піднялася. На цьому нам сказали все, пройшло і нічого не бачимо, можливо перехідний вік, як стане гірше звертайтесь. Так через місяць стало гірше, опускається ще одна повіка і додається двоїння в очах, швидка стомлюваність. Що ми пережили один Бог знає. Слава Богу що нам порадили клініку VІVERE, там ми потрапили на прийом до Макара Васильовича, чесно за пів години нам попередньо поставили діагноз (ми 4 місяці бігали по різних спеціалістах) а саме Мітохондріальна дисфункція, потрібно ще було доздавати аналізи. І відразу назначили лікування. Моєму подиву не було меж після першого прийому ліків призначених в дитини відразу стабілізувався стан очей, на протязі тижня пройшло двоїння (диплопія), дитина ожила. Відповідно ми ще лікуємось але дуже дякуємо за компетентність, уважність і правильний підхід.

Леся

Лікуємо нашого хлопчика і бачимо позитивні результати, хлопчик став краще розмовляти, з'явився апетит, з'явилось бажання пробувати нові продукти, легше реагує на все, легше домовлятися. Дякую лікарю Володимиру Михайловичу Стефанишину.

Юрій

В клинике уютно и светло. Приятно удивляет всегда быстрое реагирование на вопросы и просьбы девушек-регистраторов, их доброжелательное отношение. Ни один вопрос в вайбере не остался без ответа. Дважды были с сыном на консультации у Шейко Макара Васильевича. Неординарный, профессиональный и, в то же время, душевный, можно сказать дружеский подход, к решению проблем пациента, у Макара Васильевича. Также 2 года назад мы были на приеме у иммунолога Мельник Леси Игоревны. Остались тоже очень довольны. Впечатлило глубокое понимание проблемы, а также достаточно доступное объяснение и интересное изложение информации.

Елена Моцарь

Доброго дня! Нарешті я написала відгук, вже півроку з вами) Я мама дитини, яка до 18 років мала купу діагнозів, які і близько не мали відношення до нашої хвороби! Уявіть, скільки часу було витрачено... лікування ніяке (звісно) не допомагало, а ставало ще гірше. Доки нам не порекомендували Шейко Макар Васильовича! Сказати, що Він нам допоміг , це нічого не сказати! Макар Васильович врятував мою Софію! Завдяки правильній діагностиці, ми маємо НАШ діагноз (рідке орфанне захворювання) і правильне лікування. Я бачу поліпшення, моя дитина як заново народилася! Макар Васильович - це дбайлива і дуже чутна Людина, якій довіряєш! На прийомі немає оцього бар'єру лікар-пацієнт, ви як прийшли до друга, який вас підбадьорить, вислухає. Дуже рекомендую!

Анна
Volodymyr Monastyrsky
My motto in life is to do everything consciously, in a structured way, and with maximum attention to the process. Neurology is a specialty where details are important.

- Parkinson's disease; - epilepsy and seizure syndromes; - multiple sclerosis and encephalomyelitis; - vascular neurology (strokes and their consequences, cerebral atherosclerosis, arterial hypertension); - demyelinating, inflammatory, and degenerative diseases of the nervous system; - dementia; - the effects of a traumatic brain injury; - migraine; - polyneuropathy; - neuroinfections; - encephalitis and its consequences.

Volodymyr Monastyrsky
Neurologist of the highest category, candidate of medical sciences

Stage: 20 years

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Bukulova Nana
Responsibility, structure, individual approach to everyone.

- irritable bowel syndrome - helminthiasis - inflammatory bowel diseases (Crohn's disease, ulcerative colitis) - constipation - diarrheal syndrome - digestive diseases - congenital intestinal anomalies

Bukulova Nana
Gastroenterologist, pediatric gastroenterologist, pediatrician, ultrasound diagnostician, candidate of medical sciences

Stage: 17 years

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Makar Sheiko
Changing Psychiatry Together

The doctor is now helping not only our patients but also our country. We support him and look forward to his return!

Makar Sheiko
Medical Director of VIVERE Clinic Highest-category psychiatrist and geneticist

Stage: 20 years

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Maria Stusik
Professionalism, human relations, unity of the team with the desire and aspiration to work for a good result - this is the most important thing.

- Complete (comprehensive) management of patients with herpesvirus infections, mixed infections and infectious diseases accompanied by neurological disorders in children with the inclusion of parents in the treatment process; - prescription of diet therapy for patients of different ages with a chronic course of infectious diseases; - prevention of recurrence of infections and exacerbation of inflammatory processes.

Maria Stusik
Highest-category pediatrician, gastroenterologist

Stage: 26 years

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Volodymyr Stefanyshyn
If you want to go fast, go by yourself; if you want to go far and confidently, go with a team. Only with a team of like-minded people you can achieve high results.

PANS/PANDAS Mitochondrial disorders Chronic fatigue syndrome Autoimmune encephalitis

Volodymyr Stefanyshyn
Director of the Medical Center, President of the Association of Neuroimmunologists of Ukraine

Stage: 22 years

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Vivere International is a chance for every patient from every corner of the world to get expert help in diagnosing and treating such diseases as autism spectrum disorders, PANS/PANDAS syndrome, chronic fatigue syndrome, depression-anxiety disorders, autoimmune encephalitis, dementia, and other diseases caused by metabolic and neuroimmunological disorders in children and adults.

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Multiple Sclerosis

Multiple Sclerosis – What Is This Disease?

Multiple sclerosis (MS) is a condition that can lead to disability and serious difficulties in daily life and communication. It is the most common immune-mediated inflammatory demyelinating disease, in which an autoimmune reaction is triggered against the myelin sheath surrounding nerves. This leads to disrupted transmission of impulses between the brain and the rest of the body. At the same time, axonal damage occurs. Imaging studies show multifocal lesions in the brain and spinal cord.

 

Causes of Multiple Sclerosis

The disease mainly affects people aged 20 to 40, although cases have been reported in older individuals and children. Women are affected twice as often as men, except for the primary progressive form. The pathology is caused by multiple mechanisms, such as inflammation, demyelination, and axonal degeneration.

However, the exact cause of multiple sclerosis has not yet been established.

Identified risk factors include:

   - Early smoking.

   - Obesity during adolescence.

   - Low levels of vitamin D3.

   - Infectious mononucleosis.

   - Infection caused by the Epstein-Barr virus.

Genetic factors also play an important role.

 

Multiple Sclerosis – Symptoms and Clinical Presentation

The disease is characterized by a relapsing course with periods of remission. Neurological manifestations are predominant.

Multiple sclerosis signs and symptoms:

   - Double vision.

   - Tingling sensations and numbness in the limbs, trunk, and face.

   - Lhermitte’s sign.

   - Muscle weakness.

   - Increased muscle tone.

   - Impaired superficial sensitivity.

   - Gait and balance disturbances.

   - General weakness.

   - Body pain.

   - Dizziness.

   - Erectile dysfunction, decreased libido.

   - Cognitive impairment.

   - Depressive states.

Loss of sphincter control is particularly distressing for patients.

 

Multiple Sclerosis – Diagnosis and Detection Methods

For an accurate diagnosis, it is recommended to contact the specialists at VIVERE CLINIC. Practicing neuroimmunologists can identify demyelinating lesions in characteristic areas using advanced equipment.

MS diagnosis includes:

   - Magnetic resonance imaging (MRI) of the brain.

   - Assessment of clinical symptoms.

   - Analysis of medical history.

   - Blood tests using PCR and antibody detection for viruses.

Additionally, the doctor may order an examination of cerebrospinal fluid obtained via lumbar puncture.

 

Vivere – A Clinic for Treating Multiple Sclerosis with Excellent Results

In medical practice, MS is considered an incurable disease. The goal of treatment is to relieve symptoms and exacerbations and to modify the course of the disease. Therapy can be initiated in patients at high risk of developing the condition.

Multiple sclerosis treatment aims to reduce and eliminate neurological symptoms and is tailored to the severity of the clinical presentation.

For this purpose, the following are used:

   - Glucocorticosteroids administered orally (prednisolone) or intravenously (methylprednisolone).

   - If this is ineffective, plasmapheresis may be prescribed.

   - When standard therapy is contraindicated, for example due to comorbidities or pregnancy, immunoglobulins are used.

Symptomatic treatment is often the most appropriate approach.

A specialist may prescribe:

   - Muscle relaxants.

   - Antidepressants.

   - Pain relievers from the antiepileptic group (carbamazepine).

   - Medications affecting bladder function (oxybutynin, tolterodine).

   - Drugs to improve sexual function (estrogens for women, sildenafil and tadalafil for men).

   - Agents regulating bowel movements (osmotic agents, fiber).

An important part of a comprehensive approach to achieving stable remission is physical rehabilitation and psychotherapy. Success depends primarily on the clinical form, timing of therapy initiation, and individual patient characteristics.