MITOSWAB™ — is a unique tool used to diagnose mitochondrial dysfunction.

What is MitoSWAB™ (MitoSwab)?

MitoSWAB™ Plus is the first and only «non-invasive» assessment test for the study of mitochondrial dysfunction, analyzing components of the electron transport chain – complex I, II, III, and IV.

Why does it matter?
Mitochondrial disorders can occur at any age and in most cases affect both sexes equally.
Knowing the functional capacity of the mitochondria is vital to managing overall health. An effective assessment of the impairment can help initiate treatment in time.

What are the signs and symptoms of mitochondrial diseases?

  • fatigue;
  • growth retardation;
  • learning problems;
  • physical activity intolerance;
  • muscle weakness;
  • loss of muscle coordination;
  • neurological symptoms;
  • gastrointestinal symptoms;
  • heart failure;
  • deafness;
  • blindness.

What happens when mitochondria don't function properly?
Studies show that mitochondrial dysfunction can be a prerequisite for many neurological disorders. Also, clinical signs of mitochondrial disorders can involve either a single organ or any combination of organ systems. 

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Mitochondrial dysfunction manifests itself as follows:

  • autism spectrum disorder ASD;
  • Parkinson's disease;
  • dementia;
  • bipolar disorder;
  • schizophrenia;
  • depression;
  • diabetes mellitus;
  • asthma;
  • chronic fatigue syndrome;
  • cramps;
  • gastrointestinal problems;
  • heart and kidney problems;
  • mitochondrial disease;
  • Ley's disease;
  • Leber hereditary optical neuropathy (LHON);
  • autosomal dominant optic atrophy (ADOA);
  • pyruvate dehydrogenase deficiency;
  • other genetic disorders such as Alpers syndrome, Bart's syndrome, carnitine deficiency, complex I, II, III, IV, V deficiency, coenzyme Q10 deficiency, MELAS, etc.

How does the MITOSWAB test help you? 

MITOSWAB™ is a unique tool that is used to diagnose mitochondrial dysfunction. It is also a valuable method that can be used to monitor the effectiveness of prescribed therapy. MITOSWAB™ has an 84% correlation with muscle biopsy, which is considered the gold standard for diagnosing mitochondrial dysfunction. However, muscle biopsy is invasive (painful and difficult). MITOSWAB™ is an excellent alternative as a potential first-line test for mitochondrial dysfunction.

How is the test done?
The test is done with an oral swab (the inside of the cheeks – left and right). It is a simple procedure that is quick and easy to perform. You can do the sampling at home at your convenience. You can perform the procedure in our clinic or we can send you a kit with instructions for convenient biomaterial sampling at home. 

How to prepare for the analysis?
If you are taking certain medications on an ongoing basis, please consult your physician for advice. Because some medications/supplements can interfere with mitochondrial function.

1 hour before taking the material, clean the mouth by gently rinsing it with plain water (if the child is not able to rinse his mouth, then just let him drink water). Make sure there is no food. Wait 30 minutes if you have brushed your teeth.

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