Chronic inflammatory demyelinating polyneuropathy

Chronic inflammatory demyelinating polyneuropathy is a pathology that is accompanied by the simultaneous involvement of a large number of peripheral nerves in different anatomical areas and progressive muscle weakness, which develops over 8 weeks or longer. It develops due to autoimmune reactions, in which the myelin layer around the nerves is damaged.
Statistically, CIDP affects middle-aged men more often. In adults, it is diagnosed at a rate of 1-2 cases per 100,000 people. After the age of 50, the pathology progresses faster, has a more severe course, and responds worse to therapy.

Symptoms

At the initial stage, CIDP is difficult to detect because it is not accompanied by any signs. As the myelin sheath of the peripheral nerves becomes more extensive, the patient becomes disturbed by muscle weakness in the extremities (in the legs or simultaneously in the legs and arms). As in Guillain-Barré syndrome, the symptom increases, but the process lasts longer than 8 weeks.

Weakness is pronounced and may be accompanied by a tingling sensation or numbness. The symptom manifests itself irregularly - it may intensify, then weaken, and then increase again.
Cardiac rhythm abnormalities, BP fluctuations, vegetative disorders are sometimes observed, but such changes are less frequent and less pronounced than in Guillain-Barre syndrome.

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Reasons

The main cause of chronic inflammatory demyelinating polyneuropathy is an autoimmune reaction. The immune system mistakenly causes the body to attack its own tissues, leading to the gradual destruction of myelin and impaired nerve conduction.

Infections, systemic autoimmune diseases can provoke the pathological process. The risk also increases if a person has a hereditary predisposition.

Diagnostic methods

The diagnosis is made based on the clinical picture and examination findings. At the VIVERE CLINIC, patients undergo a comprehensive diagnosis, which allows us to evaluate the extent of damage to the peripheral nervous system and find the cause of the autoimmune reaction. Only this approach makes it possible to achieve significant mitigation of the manifestations of the disease, restoration of functions, and prevention of complications.

In order to confirm the diagnosis of CIDP, the following is prescribed:
    • electromyography;
    • nerve conduction study;
    • Laboratory tests that can confirm an autoimmune reaction and find its root cause;
    • blood tests for antibodies to gangliosides, anti-MAG.

All necessary diagnostic services, including specific tests, are available at our clinic. You can get tested quickly and without having to go to several laboratories.

Prevention

Specific methods of preventing CIDP have not been developed. Timely and correct treatment of infections, autoimmune diseases can reduce the risk of pathology development.

Treatment

Therapy is developed individually for each clinical case. Our physicians have extensive practical experience in the management of patients with this diagnosis and have the necessary knowledge to select the treatment that addresses the cause and achieves a significant improvement in the patient's condition.

Chronic inflammatory demyelinating polyneuropathy is treated with medication. 
The combination of drugs and their dosage are chosen personally. Plasmapheresis may also be used if medication is not effective.
CIDP may require long-term therapy. However, our physicians are able to find treatments that help achieve a noticeable improvement in the patient's condition in just a short period of time.

Recommendations

The disease is more amenable to therapy if it is started at the right time. Therefore, if you are worried about even a slight weakness in the body, do not put off making an appointment with a doctor. Visit the VIVERE CLINIC and our specialists will find the cause of your condition and choose effective methods to restore your health.

Cost

The cost of treatment for CIDP depends on its duration and the techniques used. 
You can schedule an appointment with the VIVERE CLINIC by phone or by filling out the online form on our website. 

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