Epilepsy due to cerebral folate deficiency is caused by the impaired supply of the substance 5-MTHF to the brain tissue, which in some cases causes the development of seizures. The pathology is associated with metabolic disorders and requires specific treatment aimed at eliminating the root cause.
Symptoms
Epilepsy against the background of CFD is accompanied by myoclonic seizures. Symmetrical asynchronous muscle twitches may extend to the whole body or to some of its parts (arms, upper torso). Sometimes the patient falls sharply during the paroxysm, after which the seizure ends and the patient stands up.
Some attacks are accompanied by an increase in body temperature. The patient also experiences increased fatigue and emotional exhaustion. The development of this form of disease in children is associated with a high risk of impaired physical and psycho-emotional development. Therefore, the slightest deviation in the child's well-being should be a reason to consult a specialist.
If you notice periodic muscle twitching in your child's body, do not hesitate to visit your doctor. In the initial stages and in early childhood, the pathology is best corrected, between the ages of 2-5 years, there is a high chance of recovery.
Reasons
This form of epilepsy develops against a background of cerebral folate deficiency, which is due to a genetic factor and is often associated with serious metabolic disorders in the body. For example, CFN can accompany Kearns-Seyre syndrome and other mitochondrial dysfunctions. In this case, there is impaired transport of folate through the vascular system, which leads to impaired absorption and, consequently, deficiency.
