Epilepsy due to cerebral folate deficiency

Epilepsy due to cerebral folate deficiency is caused by the impaired supply of the substance 5-MTHF to the brain tissue, which in some cases causes the development of seizures. The pathology is associated with metabolic disorders and requires specific treatment aimed at eliminating the root cause.

Symptoms

Epilepsy against the background of CFD is accompanied by myoclonic seizures. Symmetrical asynchronous muscle twitches may extend to the whole body or to some of its parts (arms, upper torso). Sometimes the patient falls sharply during the paroxysm, after which the seizure ends and the patient stands up.

Some attacks are accompanied by an increase in body temperature. The patient also experiences increased fatigue and emotional exhaustion. The development of this form of disease in children is associated with a high risk of impaired physical and psycho-emotional development. Therefore, the slightest deviation in the child's well-being should be a reason to consult a specialist.

If you notice periodic muscle twitching in your child's body, do not hesitate to visit your doctor. In the initial stages and in early childhood, the pathology is best corrected, between the ages of 2-5 years, there is a high chance of recovery.

Reasons

This form of epilepsy develops against a background of cerebral folate deficiency, which is due to a genetic factor and is often associated with serious metabolic disorders in the body. For example, CFN can accompany Kearns-Seyre syndrome and other mitochondrial dysfunctions. In this case, there is impaired transport of folate through the vascular system, which leads to impaired absorption and, consequently, deficiency.

For an appointment or consultation, call:

Diagnostic methods

At VIVERE, when epilepsy is suspected to be due to cerebral folate deficiency, each patient undergoes a comprehensive examination. It allows you to determine the form and cause of the pathology, to identify the triggers for the onset of seizures, as well as to choose an effective treatment.

The study includes:
    • comprehensive laboratory diagnostics;
    • FRAT;
    • MitoSwab.

Our specialists look for the cause of epilepsy to treat it and thus achieve a sustained remission or even complete recovery if this is possible in a particular clinical case.

Prevention

To reduce the risk of epilepsy due to cerebral folate deficiency in children, pregnancy planning and its correct management can help. It is also recommended to detect and correct metabolic disorders in a timely manner.

Treatment

  • To begin treatment, VIVERE CLINIC specialists first look for the cause of the pathology in order to act on the mechanism of its occurrence. In most cases, medications are prescribed. Drugs are chosen to replenish folate deficiency, improve metabolic processes, normalize brain functions, etc.
  • Our patients receive lifelong support from a specialized neurologist-epileptologist. Treatment can take place on an outpatient basis or in a day hospital.
BOOK AN APPOINTMEN

Recommendations

Epilepsy caused by CFD requires mandatory therapy and monitoring of the patient's condition to reduce the frequency of seizures and prevent irreversible changes in the brain. Timely therapy can significantly improve the patient's quality of life, so you should make an appointment with your doctor when you see the first signs.

Cost

The price of diagnosis and treatment in our clinic depends on the list of necessary services and is determined individually for each patient.
To schedule, your initial consultation with VIVERE CLINIC call us or leave an online request online and our manager will contact you.

DO YOU NEED A HELP?

Call or request an appointment now

BOOK AN APPOINTMEN

Our mission is to change attitudes toward «doomed» diagnoses and to give each patient hope and a chance for a full and high-quality life.

BOOK AN APPOINTMEN

Лікуємо нашого хлопчика і бачимо позитивні результати, хлопчик став краще розмовляти, з'явився апетит, з'явилось бажання пробувати нові продукти, легше реагує на все, легше домовлятися. Дякую лікарю Володимиру Михайловичу Стефанишину.

Юрій

В клинике уютно и светло. Приятно удивляет всегда быстрое реагирование на вопросы и просьбы девушек-регистраторов, их доброжелательное отношение. Ни один вопрос в вайбере не остался без ответа. Дважды были с сыном на консультации у Шейко Макара Васильевича. Неординарный, профессиональный и, в то же время, душевный, можно сказать дружеский подход, к решению проблем пациента, у Макара Васильевича. Также 2 года назад мы были на приеме у иммунолога Мельник Леси Игоревны. Остались тоже очень довольны. Впечатлило глубокое понимание проблемы, а также достаточно доступное объяснение и интересное изложение информации.

Елена Моцарь

Доброго дня! Нарешті я написала відгук, вже півроку з вами) Я мама дитини, яка до 18 років мала купу діагнозів, які і близько не мали відношення до нашої хвороби! Уявіть, скільки часу було витрачено... лікування ніяке (звісно) не допомагало, а ставало ще гірше. Доки нам не порекомендували Шейко Макар Васильовича! Сказати, що Він нам допоміг , це нічого не сказати! Макар Васильович врятував мою Софію! Завдяки правильній діагностиці, ми маємо НАШ діагноз (рідке орфанне захворювання) і правильне лікування. Я бачу поліпшення, моя дитина як заново народилася! Макар Васильович - це дбайлива і дуже чутна Людина, якій довіряєш! На прийомі немає оцього бар'єру лікар-пацієнт, ви як прийшли до друга, який вас підбадьорить, вислухає. Дуже рекомендую!

Анна

По аналізам у дитини герпес 6 типу, звернулись в клініку до імунолога Лесі Мельник на консультацію, лікар професійно все пояснила та назначила курс лікування.

Наталія

Дуже задоволений фаховим спеціалістом Монастирським В. О. Спеціаліст вищої категорії з величезним досвідом лікування. Уважний, компетентний, фаховий невропатолог, нейроімунолог. Моя подяка Володимиру Олеговичу.

Олександр
Andrii Senchenko
Balance in everything!

- Abdominal ultrasound - Thyroid ultrasound - Ultrasound of pelvic organs - Ultrasound of the kidneys

Andrii Senchenko
Category II ultrasound doctor

Stage: 10 years

BOOK AN APPOINTMEN
Daria Arsiriy
There are things that do not depend on us, but that does not mean that this is the end of life. We have to act, look for solutions, exhale, and look at the situation from a different angle.

I diagnose and treat patients with lesions of the central, peripheral, and autonomic nervous system. Possess the following manipulations: - paravertebral blockade; - kinesiotaping; - lumbar puncture.

Daria Arsiriy
Category II neurologist, a pediatric neurologist

Stage: 10 years

BOOK AN APPOINTMEN
Lesya Melnyk
Do what you love, and you'll never have to work.

Treatment of children with ASD PANS/PANDAS/PITANS treatment Treatment of opportunistic infections Treatment of immune deficiencies Treatment of dermatoses of various etiologies (acne, rosacea, dermatitis) Treatment of fungal and viral diseases (herpes, warts, molluscum contagiosum), allergic dermatosis, streptoderma, eczema, atopic dermatitis Treatment and support of chronic dermatoses in order to prolong remission periods and reduce the number of relapses

Lesya Melnyk
Immunologist, pediatric immunologist, Dermatologist (adult and pediatric)

Stage: 4 years

BOOK AN APPOINTMEN
Makar Sheiko
Changing Psychiatry Together

- counseling appointment; - pathopsychological examination; - treatment of mental and behavioral disorders.

Makar Sheiko
Medical Director of VIVERE Clinic Highest-category psychiatrist and geneticist

Stage: 20 years

BOOK AN APPOINTMEN
Olga Selezneva
The first step toward solving a problem is to realize that it exists

Electroencephalography (EEG) in children and adults for differential diagnosis of seizures and epileptiform states in various diseases, as well as dynamic monitoring during specific therapy.

Olga Selezneva
Functional diagnostics doctor of the highest category, neurologist

Stage: 34 years

BOOK AN APPOINTMEN

NEED A SPECIALIST CONSULTATION?

OUR CLINIC FOR THE WORLD

Vivere International is a chance for every patient from every corner of the world to get expert help in diagnosing and treating such diseases as autism spectrum disorders, PANS/PANDAS syndrome, chronic fatigue syndrome, depression-anxiety disorders, autoimmune encephalitis, dementia, and other diseases caused by metabolic and neuroimmunological disorders in children and adults.

  • A full range of services «Medical Tourism» is developed for foreign nationals.
  • We offer consulting services of leading highly specialized specialists of Ukraine and the world in Ukrainian, English, or any other foreign language.
  • We provide the opportunity to take or send your tests to any laboratory in the world.
  • We offer medical assistance (full complex) to Ukrainian patients who are abroad.
  • We offer «Day Hospital» service for the administration of any drugs registered in Ukraine. 

Our clinic has a multidisciplinary team of professionals, who use the latest evidence-based treatment protocols that have proven to be effective.

VIVERE INTERNATIONAL

  • Canada
  • USA
  • Ireland
  • Portugal
  • United Kingdom
  • Spain
  • Netherlands
  • Belgium
  • Germany
  • Switzerland
  • Italy
  • Czech Republic
  • Austria
  • Croatia
  • Bosnia and Herzegovina
  • Albania
  • Greece
  • Hungary
  • Serbia
  • North Macedonia
  • Sweden
  • Finland
  • Poland
  • Belarus
  • Moldova
  • Ukraine
  • Turkey
  • Cyprus
  • Georgia
  • Azerbaijan
  • Saudi Arabia
  • UAE
  • Kazakhstan
  • Uzbekistan
  • South Korea
  • Australia
12000+
provided professional advice
8244+
patients sought our help and support
1015+
foreign patients
9000+
diagnostic tests were performed
Canada
USA
Ireland
Portugal
United Kingdom
Spain
Netherlands
Belgium
Germany
Switzerland
Italy
Czech Republic
Austria
Croatia
Bosnia and Herzegovina
Albania
Greece
Hungary
Serbia
North Macedonia
Sweden
Finland
Poland
Belarus
Moldova
Ukraine
Turkey
Cyprus
Georgia
Azerbaijan
Saudi Arabia
UAE
Kazakhstan
Uzbekistan
South Korea
Australia

  • Canada
  • USA
  • Ireland
  • Portugal
  • United Kingdom
  • Spain
  • Netherlands
  • Belgium
  • Germany
  • Switzerland
  • Italy
  • Czech Republic
  • Austria
  • Croatia
  • Bosnia and Herzegovina
  • Albania
  • Greece
  • Hungary
  • Serbia
  • North Macedonia
  • Sweden
  • Finland
  • Poland
  • Belarus
  • Moldova
  • Ukraine
  • Turkey
  • Cyprus
  • Georgia
  • Azerbaijan
  • Saudi Arabia
  • UAE
  • Kazakhstan
  • Uzbekistan
  • South Korea
  • Australia