Immune-dependent forms of epilepsy

Immune-dependent forms of epilepsy are diagnosed in about 5-35% of patients with this diagnosis. They are caused by dysfunction of the immune system and appear in the form of seizures that can last from a few days to 2-3 weeks.

Patients who suffer from other immunological pathologies, such as autoimmune thyroiditis, lupus erythematosus, polymyositis, rheumatoid arthritis, scleroderma, etc. are more likely to develop autoimmune epilepsy (AE). The risk also increases if there are similar pathologies in close relatives.
In AEs, antibodies are synthesized in the body that attack the brain, which can provoke seizures.

Symptoms

The main manifestation of immune-mediated epilepsy is frequent prolonged seizures. Seizures may also be accompanied by hyperthermia. Other characteristic manifestations of this form of the disease:
cramps spread to one part of the face and the arm on the same side;
memory impairment;
it is not always possible to control seizures with anticonvulsants;
personality disorder;
behavioral disorders — apathy, the tendency to depression, paranoid thoughts, hallucinations.

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Reasons

Autoimmune epilepsy was isolated and included in the generally accepted classification not so long ago. The causes of its development may be:
    • herpesvirus infection
    • other autoimmune pathologies in the patient;
    • a history of family history;
    • brain tumor.

Diagnostic methods

It is the identification of the cause of seizures that plays a key role in choosing an effective treatment tactic. That is why at the VIVERE CLINIC patients undergo a comprehensive examination to determine exactly what factors provoke seizures and select further treatment.

The following methods may be prescribed for the examination of the patient:

    • electroencephalography;
    • laboratory tests;
    • MRI of the brain;
    • autoimmune encephalitis testing (NMDA antibodies, antibodies to glycine receptors, potassium channels, GABA, AMPA, GAD-65, antibodies to neurons, etc.).

A wide range of diagnostic procedures can be performed at our medical center. The patient does not need to visit several laboratories for specific tests. A multidisciplinary team works with the patient: psychiatrist, neurologist, epileptologist, immunologist.

Prevention and Treatment

  • There are no specific methods for preventing AEs. Patients with autoimmune pathologies should not neglect their timely treatment. If there are relatives with such diseases in the family, it is also necessary to closely monitor their health and at the first signs of epilepsy make an appointment for a consultation with a doctor.
  • Multiple studies prove that immunotherapy and hormone therapy (immunoglobulins, steroids are used) show good results in autoimmune epilepsy. If the condition is caused by a brain tumor, it is necessary to focus on its treatment. Our doctors also pay attention to the general health of the patient and select etiological therapy in the presence of autoimmune pathologies.
  • This approach makes it possible to achieve a rapid cessation of recurrent seizure episodes and prevent damage to brain cells.
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Recommendations

Timely and correct treatment of autoimmune epilepsy is able to stop the pathological process and achieve complete recovery of the patient. Therefore, it is important not to neglect the first symptoms of AE and immediately go to the doctor when they appear.

Cost

At VIVERE, patients can receive the necessary diagnostic services and treatment according to international protocols. The price depends on the diagnostic methods used and the duration of the therapy.
You can make an appointment for a consultation at our medical center by using the form on our website or by phone.

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Лікуємо нашого хлопчика і бачимо позитивні результати, хлопчик став краще розмовляти, з'явився апетит, з'явилось бажання пробувати нові продукти, легше реагує на все, легше домовлятися. Дякую лікарю Володимиру Михайловичу Стефанишину.

Юрій

В клинике уютно и светло. Приятно удивляет всегда быстрое реагирование на вопросы и просьбы девушек-регистраторов, их доброжелательное отношение. Ни один вопрос в вайбере не остался без ответа. Дважды были с сыном на консультации у Шейко Макара Васильевича. Неординарный, профессиональный и, в то же время, душевный, можно сказать дружеский подход, к решению проблем пациента, у Макара Васильевича. Также 2 года назад мы были на приеме у иммунолога Мельник Леси Игоревны. Остались тоже очень довольны. Впечатлило глубокое понимание проблемы, а также достаточно доступное объяснение и интересное изложение информации.

Елена Моцарь

Доброго дня! Нарешті я написала відгук, вже півроку з вами) Я мама дитини, яка до 18 років мала купу діагнозів, які і близько не мали відношення до нашої хвороби! Уявіть, скільки часу було витрачено... лікування ніяке (звісно) не допомагало, а ставало ще гірше. Доки нам не порекомендували Шейко Макар Васильовича! Сказати, що Він нам допоміг , це нічого не сказати! Макар Васильович врятував мою Софію! Завдяки правильній діагностиці, ми маємо НАШ діагноз (рідке орфанне захворювання) і правильне лікування. Я бачу поліпшення, моя дитина як заново народилася! Макар Васильович - це дбайлива і дуже чутна Людина, якій довіряєш! На прийомі немає оцього бар'єру лікар-пацієнт, ви як прийшли до друга, який вас підбадьорить, вислухає. Дуже рекомендую!

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Наталія

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